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Spine (Phila Pa 1976) 24 (23), 24192425

Med 79, 207214 (2022)

This limitation does not undermine the studys value in identifying a novel regulatory axis but highlights the need for follow-up experiments to strengthen mechanistic claims

In the course of the experiments, tert-butyl hydroperoxide (TBHP) was used to induce oxidative stress in annulus fibrosus cells (AFCs) and nucleus pulposus cells (NPCs)

SLC7A11 plays an antioxidant role by supporting GSH generation via cystine import (66)

Research demonstrated that immunological targeting by HSPs could be a potential pathogenic mechanism of neuropathy following SARS-CoV-2 infection [33]